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Article

Hepatocellular Carcinoma Immune Landscape and the Potential of Immunotherapies.

Frontiers in immunology - 1 Jan 2021

Giraud Julie, Chalopin Domitille, Blanc Jean-Frédéric, Saleh Maya

Abstract excerpt

Hepatocellular carcinoma (HCC) is the most common liver tumor and among the deadliest cancers worldwide. Advanced HCC overall survival is meager and has not improved over the last decade despite approval of several tyrosine kinase inhibitors (TKi) for first and second-line treatments. The recent approval of immune checkpoint inhibitors (ICI) has revolutionized HCC palliative care. Unfortunately, the majority of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33815418
DOI: 10.3389/fimmu.2021.655697
PMCID: PMC8012774

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