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Article

TREM1 <sup>+</sup> regulatory myeloid cells expand in steatohepatitis-HCC and associate with poor prognosis and therapeutic resistance to immune checkpoint blockade

2022-11-10

Abstract excerpt

<h4>ABSTRACT</h4> Hepatocellular carcinoma (HCC) is an inflammation-associated cancer arising from viral and non-viral etiologies. Immune checkpoint blockade primarily benefits patients with viral HCC. Expansion of suppressive myeloid cells is a hallmark of chronic inflammation and cancer, but their heterogeneity in HCC is not fully resolved and might underlie immunotherapy resistance in the steatohepatitis setti...

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Literature Corpus work
adcbafdc-30a7-5c12-bd76-c049254a3db4
DOI
10.1101/2022.11.09.515839
Open publication

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