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Article

Histamine H4 receptor polymorphism: a potential predictor of risperidone efficacy.

Journal of clinical psychopharmacology - 1 Apr 2013

Wei Zhiyun, Wang Lei, Yu Tao, Wang Yang, Sun Liya, Wang Ti, Huo Ran, Li Yang, Wu Xi, Qin Shengying, Xu Yifeng, Feng Guoyin, He Lin, Xing Qinghe

Abstract excerpt

Histamine interacts with histamine H4 receptor (HRH4) to impact antipsychotic response. Pharmacogenetic information about this receptor could therefore be useful in developing individualized therapy. The aim of this investigation was to clarify whether polymorphisms at human HRH4 gene alter risperidone efficacy. We genotyped 5 tag-single nucleotide polymorphisms of the HRH4 gene and analyzed their association...

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Source

Identifiers

PMID: 23422377
DOI: 10.1097/JCP.0b013e318283963b

Genes

HRH4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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