Article
Histamine H4 receptor gene polymorphisms: a potential predictor of oral H1 antihistamine efficacy for allergic rhinitis.
International forum of allergy & rhinology - 1 Mar 2017
Gu Jian, Mao Xiao-Hui, Yang Xi-Zhi, Ao Hua-Fei, Zhang Zhe, Li You
Abstract excerpt
BACKGROUND: Our study aimed to investigate the associations between Histamine H4 receptor (HRH4) gene polymorphisms (rs77485247, rs74604924, and rs77041280) and oral H1 antihistamine efficacy for the treatment of allergic rhinitis (AR) patients. METHODS: A total of 142 AR patients were selected as a case group and 160 healthy individuals were recruited as a control group. Single nucleotide polymorphisms (SNPs) in...
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