Article
Association between a polymorphism of the HTR3A gene and therapeutic response to risperidone treatment in drug-naive Chinese schizophrenia patients.
Pharmacogenetics and genomics - 1 Aug 2008
Gu Bo, Wang Lei, Zhang Ai-Ping, Ma Gang, Zhao Xin-Zhi, Li Hua-Fang, Feng Guo-Ying, He Lin, Xing Qing-He
Abstract excerpt
OBJECTIVES: Certain components of the serotonin system have been known for some time to be risk factors for schizophrenia. Few studies have, however, focused on the association between the therapeutic responses to atypical antipsychotics, such as risperidone, and polymorphisms of the 5-HT3 receptor, the only ionotropic ligand-gated serotonin receptor, even though there have been some genetic clues linking HTR3A...
Topics
Join the communities discussing this publication.