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Article

Genetic association study of treatment response with olanzapine/fluoxetine combination or lamotrigine in bipolar I depression.

The Journal of clinical psychiatry - 1 May 2010

Perlis Roy H, Adams David H, Fijal Bonnie, Sutton Virginia K, Farmen Mark, Breier Alan, Houston John P

Abstract excerpt

OBJECTIVE: To evaluate common genetic variations for association with symptomatic improvement in bipolar I depression following treatment with olanzapine/fluoxetine combination (OFC) or lamotrigine. METHOD: Symptom improvement was assessed in 88 OFC-treated and 85 lamotrigine-treated white patients with bipolar I depression in the 7-week acute period of a randomized, double-blind study comparing OFC (6/25, 6/50,...

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Source

Identifiers

PMID: 20021991
DOI: 10.4088/JCP.08m04632gre

Genes

HRH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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