Article
Association of risperidone treatment response with a polymorphism in the 5-HT(2A) receptor gene.
The American journal of psychiatry - 1 Sept 2002
Lane Hsien-Yuan, Chang Yue-Cune, Chiu Chih-Chiang, Chen Mao-Liang, Hsieh Min-Hua, Chang Wen-Ho
Abstract excerpt
OBJECTIVE: This study investigated the effect of the 102-T/C polymorphism in the 5-HT(2A) receptor gene on risperidone efficacy. METHOD: One hundred Han Chinese patients with acutely exacerbated schizophrenia were given risperidone for up to 42 days. The patients were genotyped for 5-HT(2A) polymorphisms. Psychopathology was measured biweekly with the Positive and Negative Syndrome Scale while the patients were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
