Article
Association analysis of serotonin receptor 7 gene (HTR7) and risperidone response in Chinese schizophrenia patients.
Progress in neuro-psychopharmacology & biological psychiatry - 30 Apr 2009
Wei Zhiyun, Wang Lei, Xuan Jiekun, Che Ronglin, Du Jing, Qin Shengying, Xing Yi, Gu Bo, Yang Lun, Li Huafang, Li Jun, Feng Guoyin, He Lin, Xing Qinghe
Abstract excerpt
Several lines of evidence suggest that the human 5-HT(7) receptor may be involved in the pharmacodynamics of risperidone and may influence clinical response of the drug. A pharmocogenetics study of this receptor may therefore be useful in developing individualized therapy. But few studies about it have been done. In this study, we genotyped ten single nucleotide polymorphisms (SNPs) distributed throughout the...
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