Article
Pharmacogenetics analysis of serotonin receptor gene variants and clinical response to risperidone in Han Chinese schizophrenic patients.
Neuroscience letters - 14 Sept 2018
Zhou Wei, Chang Wushao, Yan Yucai, Shen Lu, Li Wenqiang, Yi Zhenghui, Qin Shengying
Abstract excerpt
Assessments of the pharmacological profiles of antipsychotic agents have shown that the serotonin receptor family is often involved in their pharmacodynamics. Response to antipsychotic therapy is highly variable, yet prognostic biomarkers are lacking. The aim of the study was to investigate the association of 14 single nucleotide polymorphisms (SNPs) selected from HTR3C, HTR3D, HTR5A and HTR6 with risperidone...
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