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Article

Paraoxonase 1 gene polymorphism does not affect clopidogrel response variability but is associated with clinical outcome after PCI.

PloS one - 1 Jan 2013

Park Kyung Woo, Park Jin Joo, Kang Jeehoon, Jeon Ki-Hyun, Kang Si-Hyuck, Han Jung-Kyu, Lee Sang Eun, Yang Han-Mo, Lee Hae-Young, Kang Hyun-Jae, Koo Bon-Kwon, Oh Byung-Hee, Park Young-Bae, Kim Hyo-Soo

Abstract excerpt

BACKGROUND: Paraoxonase (PON) is a high-density-lipoprotein (HDL) associated enzyme with antioxidative and anti-atherogenic property. Its function is associated with coronary artery disease and its activity genetically controlled. We evaluated whether genetic variation of PON-1 is associated with clinical outcome in a large cohort of Korean patients with drug-eluting stents implantation. METHODS: A total of 1676...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23418418
DOI: 10.1371/journal.pone.0052779
PMCID: PMC3572125

Genes

PON1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Paraoxonase 1 gene polymorphism does not affect clopidogrel response variability but is associated with clinical outcome after PCI.PMID 23418418Read ↗

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Association between Q192R PON1 genetic polymorphism and major adverse cardiovascular events in patients treated with clopidogrel: an updated meta-analysis.Semantic proximity Read ↗

Paraoxonase 1 (PON1) gene variants are not associated with clopidogrel response.Semantic proximity Read ↗

Paraoxonase-1 is a major determinant of clopidogrel efficacy.Semantic proximity Read ↗

Genetic determinants of clopidogrel responsiveness in Koreans treated with drug-eluting stents.Semantic proximity Read ↗

Paraoxonase-1 is not a major determinant of stent thrombosis in a Taiwanese population.Semantic proximity Read ↗

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No association of paraoxonase-1 Q192R genotypes with platelet response to clopidogrel and risk of stent thrombosis after coronary stenting.Semantic proximity Read ↗

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