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Article

Association between Q192R PON1 genetic polymorphism and major adverse cardiovascular events in patients treated with clopidogrel: an updated meta-analysis.

Expert opinion on drug safety - 1 Jan 2000

Biswas Mohitosh, Kali Sumaiya Khatun, Sarker Ashish Kumar, Sukasem Chonlaphat

Abstract excerpt

BACKGROUND: Clopidogrel's responsiveness may be affected by the paraoxonase-1 (PON1) enzyme encoded by the Q192R PON1 genetic variant. We aimed to determine the aggregated risk of MACEs associated with carrying Q192R PON1 genetic variant in patients taking clopidogrel. RESEARCH DESIGN AND METHODS: Different databases were searched systematically for eligible studies, and risk ratio (RR) was measured using RevMan...

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Identifiers

PMID: 37148265
DOI: 10.1080/14740338.2023.2212152

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Association between Q192R PON1 genetic polymorphism and major adverse cardiovascular events in patients treated with clopidogrel: an updated meta-analysis.PMID 37148265Read ↗

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