Article
Non-optimal codon usage is a mechanism to achieve circadian clock conditionality.
Nature - 7 Mar 2013
Xu Yao, Ma Peijun, Shah Premal, Rokas Antonis, Liu Yi, Johnson Carl Hirschie
Abstract excerpt
Circadian rhythms are oscillations in biological processes that function as a key adaptation to the daily rhythms of most environments. In the model cyanobacterial circadian clock system, the core oscillator proteins are encoded by the gene cluster kaiABC. Genes with high expression and functional importance, such as the kai genes, are usually encoded by optimal codons, yet the codon-usage bias of the kaiBC genes...
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