Article
Mutations in KaiA, a clock protein, extend the period of circadian rhythm in the cyanobacterium Synechococcus elongatus PCC 7942.
Microbiology (Reading, England) - 1 Sept 2002
Nishimura Hideya, Nakahira Yoichi, Imai Keiko, Tsuruhara Akiko, Kondo Hisayo, Hayashi Hiroshi, Hirai Makoto, Saito Hidehiko, Kondo Takao
Abstract excerpt
KaiA KaiB and KaiC are essential circadian clock proteins in the unicellular cyanobacterium Synechococcus elongatus PCC 7942. KaiA protein activates transcription of the kaiBC operon, which is believed to be a crucial step in the oscillating feedback loop of cyanobacteria. In this study, approximately approximately 400 mutations were introduced into kaiA by PCR-based mutagenesis, and rhythmic phenotypes of these...
Topics
- Biological Clocks
- Circadian Rhythm
- Cyanobacteria
- Gene Expression Regulation, Bacterial
- Genes, Reporter
- Luminescent Measurements
- Models, Biological
- Multigene Family
- Mutagenesis
- Mutation