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Article

CikA, a bacteriophytochrome that resets the cyanobacterial circadian clock.

Science (New York, N.Y.) - 4 Aug 2000

Schmitz O, Katayama M, Williams S B, Kondo T, Golden S S

Abstract excerpt

The circadian oscillator of the cyanobacterium Synechococcus elongatus, like those in eukaryotes, is entrained by environmental cues. Inactivation of the gene cikA (circadian input kinase) shortens the circadian period of gene expression rhythms in S. elongatus by approximately 2 hours, changes the phasing of a subset of rhythms, and nearly abolishes resetting of phase by a pulse of darkness. The CikA protein...

Topics

Alleles
Amino Acid Motifs
Amino Acid Sequence
Bacterial Proteins
Biological Clocks
Circadian Rhythm
Cyanobacteria
Gene Expression Regulation, Bacterial
Genes, Bacterial
Genes, Reporter
Luminescent Measurements

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Phenotype

Protein Kinases

Sequence Alignment

Source

Identifiers

PMID: 10926536
DOI: 10.1126/science.289.5480.765

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-10926536-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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