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Article

No transcription-translation feedback in circadian rhythm of KaiC phosphorylation.

Science (New York, N.Y.) - 14 Jan 2005

Tomita Jun, Nakajima Masato, Kondo Takao, Iwasaki Hideo

Abstract excerpt

An autoregulatory transcription-translation feedback loop is thought to be essential in generating circadian rhythms in any model organism. In the cyanobacterium Synechococcus elongatus, the essential clock protein KaiC is proposed to form this type of transcriptional negative feedback. Nevertheless, we demonstrate here temperature-compensated, robust circadian cycling of KaiC phosphorylation even without kaiBC...

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Identifiers

PMID: 15550625
DOI: 10.1126/science.1102540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

No transcription-translation feedback in circadian rhythm of KaiC phosphorylation.PMID 15550625Read ↗

Circadian rhythms in the synthesis and degradation of a master clock protein KaiC in cyanobacteria.Semantic proximity Read ↗

Revealing a two-loop transcriptional feedback mechanism in the cyanobacterial circadian clock.Semantic proximity Read ↗

Circadian clocks go in vitro: purely post-translational oscillators in cyanobacteria.Semantic proximity Read ↗

Global gene repression by KaiC as a master process of prokaryotic circadian system.Semantic proximity Read ↗

Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro.Semantic proximity Read ↗

Transcriptional autoregulation by phosphorylated and non-phosphorylated KaiC in cyanobacterial circadian rhythms.Semantic proximity Read ↗

KaiA-stimulated KaiC phosphorylation in circadian timing loops in cyanobacteria.Semantic proximity Read ↗

Analysis of KaiA-KaiC protein interactions in the cyano-bacterial circadian clock using hybrid structural methods.Semantic proximity Read ↗

A novel allele of kaiA shortens the circadian period and strengthens interaction of oscillator components in the cyanobacterium Synechococcus elongatus PCC 7942.Semantic proximity Read ↗

Loop-loop interactions regulate KaiA-stimulated KaiC phosphorylation in the cyanobacterial KaiABC circadian clock.Semantic proximity Read ↗

Protein-Protein Interactions in the Cyanobacterial Circadian Clock: Structure of KaiA Dimer in Complex with C-Terminal KaiC Peptides at 2.8 Å Resolution.Semantic proximity Read ↗

Dephosphorylation of the core clock protein KaiC in the cyanobacterial KaiABC circadian oscillator proceeds via an ATP synthase mechanism.Semantic proximity Read ↗

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