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Article

Global gene repression by KaiC as a master process of prokaryotic circadian system.

Proceedings of the National Academy of Sciences of the United States of America - 20 Jan 2004

Nakahira Yoichi, Katayama Mitsunori, Miyashita Hiroshi, Kutsuna Shinsuke, Iwasaki Hideo, Oyama Tokitaka, Kondo Takao

Abstract excerpt

A kaiABC clock gene cluster was previously identified from cyanobacterium Synechococcus elongatus PCC 7942, and the feedback regulation of kai genes was proposed as the core mechanism generating circadian oscillation. In this study, we confirmed that the Kai-based oscillator is the dominant circa...

Topics

Bacterial Proteins
Circadian Rhythm
Circadian Rhythm Signaling Peptides and Proteins
Cyanobacteria
Escherichia coli
Feedback
Genes, Bacterial
Genome, Bacterial
Models, Biological
Multigene Family
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

Repressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 14709675
DOI: 10.1073/pnas.0307411100
PMCID: PMC321775

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-14709675-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Global gene repression by KaiC as a master process of prokaryotic circadian system.PMID 14709675Read ↗

Expression of a gene cluster kaiABC as a circadian feedback process in cyanobacteria.Semantic proximity Read ↗

Transcriptional autoregulation by phosphorylated and non-phosphorylated KaiC in cyanobacterial circadian rhythms.Semantic proximity Read ↗

Two KaiA-binding domains of cyanobacterial circadian clock protein KaiC.Semantic proximity Read ↗

Circadian rhythms in the synthesis and degradation of a master clock protein KaiC in cyanobacteria.Semantic proximity Read ↗

Physical interactions among circadian clock proteins KaiA, KaiB and KaiC in cyanobacteria.Semantic proximity Read ↗

Revealing a two-loop transcriptional feedback mechanism in the cyanobacterial circadian clock.Semantic proximity Read ↗

KaiA-stimulated KaiC phosphorylation in circadian timing loops in cyanobacteria.Semantic proximity Read ↗

Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro.Semantic proximity Read ↗

No transcription-translation feedback in circadian rhythm of KaiC phosphorylation.Semantic proximity Read ↗

A novel allele of kaiA shortens the circadian period and strengthens interaction of oscillator components in the cyanobacterium Synechococcus elongatus PCC 7942.Semantic proximity Read ↗

The roles of the dimeric and tetrameric structures of the clock protein KaiB in the generation of circadian oscillations in cyanobacteria.Semantic proximity Read ↗

The recovery of KaiA's activity depends on its N-terminal domain and KaiB in the cyanobacterial circadian clock.Semantic proximity Read ↗

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