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Article

A Combined Computational and Genetic Approach Uncovers Network Interactions of the Cyanobacterial Circadian Clock.

Journal of bacteriology - 15 Sept 2016

Boyd Joseph S, Cheng Ryan R, Paddock Mark L, Sancar Cigdem, Morcos Faruck, Golden Susan S

Abstract excerpt

UNLABELLED: Two-component systems (TCS) that employ histidine kinases (HK) and response regulators (RR) are critical mediators of cellular signaling in bacteria. In the model cyanobacterium Synechococcus elongatus PCC 7942, TCSs control global rhythms of transcription that reflect an integration of time information from the circadian clock with a variety of cellular and environmental inputs. The HK CikA and the...

Topics

Bacterial Proteins
Circadian Clocks
Computer Simulation
Evolution, Molecular
Gene Expression Regulation, Bacterial
Mutation
Signal Transduction
Synechococcus

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27381914
DOI: 10.1128/JB.00235-16
PMCID: PMC4999937

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-27381914-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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