Article
Expression of a gene cluster kaiABC as a circadian feedback process in cyanobacteria.
Science (New York, N.Y.) - 4 Sept 1998
Ishiura M, Kutsuna S, Aoki S, Iwasaki H, Andersson C R, Tanabe A, Golden S S, Johnson C H, Kondo T
Abstract excerpt
Cyanobacteria are the simplest organisms known to have a circadian clock. A circadian clock gene cluster kaiABC was cloned from the cyanobacterium Synechococcus. Nineteen clock mutations were mapped to the three kai genes. Promoter activities upstream of the kaiA and kaiB genes showed circadian rhythms of expression, and both kaiA and kaiBC messenger RNAs displayed circadian cycling. Inactivation of any single...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Biological Clocks
- Circadian Rhythm
- Circadian Rhythm Signaling Peptides and Proteins
- Cloning, Molecular
- Cyanobacteria
- Feedback
- Gene Expression Regulation, Bacterial
- Genes, Bacterial