Article
Scleroderma Mesenchymal Stem Cells display a different phenotype from healthy controls; implications for regenerative medicine.
Angiogenesis - 1 Jul 2013
Cipriani Paola, Marrelli Alessandra, Benedetto Paola Di, Liakouli Vasiliki, Carubbi Francesco, Ruscitti Piero, Alvaro Saverio, Pantano Ilenia, Campese Antonio Francesco, Grazioli Paola, Screpanti Isabella, Giacomelli Roberto
Abstract excerpt
INTRODUCTION: Vascular involvement is a key feature of Systemic sclerosis (SSc). Although the pericytes/endothelial cells (ECs) cross-talk regulates vessels formation, no evidences about the pericytes contribution to ineffective angiogenesis in SSc are available. Recent findings showed similarities between pericytes and Bone Marrow Mesenchymal Stem Cells (BM-MSCs). Due to difficulties in pericytes isolation, this...
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