Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impairment of endothelial cell differentiation from bone marrow-derived mesenchymal stem cells: new insight into the pathogenesis of systemic sclerosis.

Arthritis and rheumatism - 1 Jun 2007

Cipriani P, Guiducci S, Miniati I, Cinelli M, Urbani S, Marrelli A, Dolo V, Pavan A, Saccardi R, Tyndall A, Giacomelli R, Cerinic M Matucci

Abstract excerpt

OBJECTIVE: Systemic sclerosis (SSc) is a disorder characterized by vascular damage and fibrosis of the skin and internal organs. Despite marked tissue hypoxia, there is no evidence of compensatory angiogenesis. The ability of mesenchymal stem cells (MSCs) to differentiate into endothelial cells w...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemokine CXCL12
Share to Chemokines, CXC
Share to Mesenchymal Stem Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neovascularization, Pathologic

Share to Platelet Endothelial Cell Adhesion Molecule-1

Share to Receptors, CXCR4

Share to Receptors, Vascular Endothelial Growth Factor

Share to Scleroderma, Systemic

Source

Identifiers

PMID: 17530639
DOI: 10.1002/art.22698

Genes

CXCR4
MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17530639-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impairment of endothelial cell differentiation from bone marrow-derived mesenchymal stem cells: new insight into the pathogenesis of systemic sclerosis.PMID 17530639Read ↗

Angiogenesis in systemic sclerosis: impaired expression of vascular endothelial growth factor receptor 1 in endothelial progenitor-derived cells under hypoxic conditions.Semantic proximity Read ↗

Circulating endothelial progenitor cells in systemic sclerosis: association with disease severity.Semantic proximity Read ↗

Endothelial-to-mesenchymal transition contributes to endothelial dysfunction and dermal fibrosis in systemic sclerosis.Semantic proximity Read ↗

Scleroderma Mesenchymal Stem Cells display a different phenotype from healthy controls; implications for regenerative medicine.Semantic proximity Read ↗

Update on the pathogenesis of Scleroderma: focus on circulating progenitor cellsSemantic proximity Read ↗

Cutaneous chronic graft-versus-host disease does not have the abnormal endothelial phenotype or vascular rarefaction characteristic of systemic sclerosis.Semantic proximity Read ↗

Mechanisms of vascular damage in systemic sclerosis.Semantic proximity Read ↗

Insights into the pathogenesis of systemic sclerosis based on the gene expression profile of progenitor‐derived endothelial cellsSemantic proximity Read ↗

Endothelial Cells Recruit Macrophages and Contribute to a Fibrotic Milieu in Bleomycin Lung InjurySemantic proximity Read ↗

Capillary regeneration in scleroderma: stem cell therapy reverses phenotype?Semantic proximity Read ↗

Towards an anti-fibrotic therapy for scleroderma: targeting myofibroblast differentiation and recruitmentSemantic proximity Read ↗

The Role of Vascular Endothelial Growth Factor in Systemic SclerosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.