Article

BMSC-Derived Exosomes Intervened the Pathogenic Changes of Scleroderma in Mouse Through Its microRNAs

2021-02-23

Abstract excerpt

<title>Abstract</title> <p>BackgroundSystemic sclerosis (SSc) is a disease with severe fibrosis of the skin without effective therapy. While bone marrow mesenchymal stem cell (BMSC) derived exosome was a potential stem cell-based candidate in treatment of SSc.MethodsBMSCs were isolated from the bone marrow of mouse and identified with the surface markers and multi-lineage differentiation. The exosomes were isolat...

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Literature Corpus work: 86c1f71f-7478-56e2-8252-8b11bfee4877
DOI: 10.21203/rs.3.rs-222441/v1

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