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Article

The contribution of mesenchymal transitions to the pathogenesis of systemic sclerosis

7 Jan 2020

Abstract excerpt

Systemic sclerosis (SSc) is a multifaceted connective tissue disease characterized by widespread vasculopathy and autoimmune reactions that evolve into progressive interstitial, perivascular, and vessel wall fibrosis that affects the skin and multiple internal organs. Such an uncontrolled fibrotic process gradually disrupts the physiologic architecture of the affected tissues and frequently leads to significant...

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PMID: 31922472
DOI: 10.5152/eurjrheum.2019.19081

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