Article

Update on the pathogenesis of Scleroderma: focus on circulating progenitor cells

2016-04-22

Abstract excerpt

In systemic sclerosis (SSc), the development of fibrosis seems to be a consequence of the initial ischemic process related to an endothelial injury. The initial trigger event in SSc is still unknown, but circulating progenitor cells (CPCs) might play a key role. Such cells have the ability to traffic into injury sites, exhibiting inflammatory features of macrophages, tissue remodeling properties of fibroblasts, an...

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Literature Corpus work: 95b60f34-0c3f-5a29-b0fc-83f66133baf9
DOI: 10.12688/f1000research.7986.1

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