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Article

Fine-tuning of voltage sensitivity of the Kv1.2 potassium channel by interhelix loop dynamics.

The Journal of biological chemistry - 5 Apr 2013

Sand Rheanna, Sharmin Nazlee, Morgan Carla, Gallin Warren J

Abstract excerpt

Many proteins function by changing conformation in response to ligand binding or changes in other factors in their environment. Any change in the sequence of a protein, for example during evolution, which alters the relative free energies of the different functional conformations changes the cond...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23413033
DOI: 10.1074/jbc.M112.437483
PMCID: PMC3617271

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23413033-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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