Article
Computational identification of residues that modulate voltage sensitivity of voltage-gated potassium channels.
BMC structural biology - 19 Aug 2005
Li Bin, Gallin Warren J
Abstract excerpt
BACKGROUND: Studies of the structure-function relationship in proteins for which no 3D structure is available are often based on inspection of multiple sequence alignments. Many functionally important residues of proteins can be identified because they are conserved during evolution. However, residues that vary can also be critically important if their variation is responsible for diversity of protein function...
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