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Article

High frequency of complex mutational patterns in lamivudine resistant hepatitis B virus isolates.

Journal of medical virology - 1 May 2013

Neumann-Fraune Maria, Beggel Bastian, Pfister Herbert, Kaiser Rolf, Verheyen Jens

Abstract excerpt

The evolution of hepatitis-B virus (HBV) drug resistance is characterized by the emergence of resistance conferring mutations and compensatory mutations. Therefore HBV drug-resistant isolates often harbor multiple mutations in the reverse transcriptase (RT) and corresponding mutations in the hepatitis B surface antigen (HBsAg). In this study mutational patterns of 60 HBV isolates harboring drug resistance...

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PMID: 23408582
DOI: 10.1002/jmv.23530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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