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Article

The profile of mutational clusters associated with lamivudine resistance can be constrained by HBV genotypes.

Journal of hepatology - 1 Mar 2009

Svicher Valentina, Gori Caterina, Trignetti Maria, Visca Michela, Micheli Valeria, Bernassola Martina, Salpini Romina, Gubertini Guido, Longo Roberta, Niero Fosca, Ceccherini-Silberstein Francesca, De Sanctis Giuseppe Maria, Spanò Alberto, Cappiello Giuseppina, Perno Carlo Federico

Abstract excerpt

BACKGROUND/AIMS: To investigate the different clusters of mutations associated with lamivudine resistance in HBV genotypes D and A. METHODS: HBV reverse transcriptase sequences of 89 HBV-infected patients failing lamivudine treatment were analyzed. The association of mutations with HBV genotypes was assessed by Chi-Squared test and multivariate logistic regression analysis. Covariate analysis was based on...

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Identifiers

PMID: 19041149
DOI: 10.1016/j.jhep.2008.07.038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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