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Article

Evolution of drug-resistant mutations in HBV genomes in patients with treatment failure during the past seven years (2010-2016).

Virus genes - 1 Feb 2018

Zhang Hong-Yu, Liu Long-Gen, Ye Chun-Yan, Chen Chun-Hua, Hang Shuang-Xiong, Zhu Zhen, Shen Hong-Yu, Huang Ze-Yu, Chen Wen-Yi, Xue Yuan

Abstract excerpt

The objective of this study was to analyze the prevalence of drug-resistant HBV mutants in patients with treatment failure during the past seven years (2010-2016). 4055 HBV-infected patients who underwent HBV polymerase gene mutation test from 2010 to 2016 were enrolled. The nucleos(t)ide analogues (NAs) resistance mutation positions, including rtL180, rtA181, rtT184, rtS202, rtM204, rtI233, rtN236, rtI169,...

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Share to Antiviral Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Evolution, Molecular

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Share to Hepatitis B, Chronic

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Source

Identifiers

PMID: 29119303
DOI: 10.1007/s11262-017-1518-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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