Article
Molecular characterization of a novel entecavir mutation pattern isolated from a multi-drug refractory patient with chronic hepatitis B infection.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Feb 2012
Karatayli Ersin, Karatayli Senem C, Cinar Kubilay, Gokahmetoglu Selma, Güven Kadri, Idilman Ramazan, Yurdaydin Cihan, Bozdayi A Mithat
Abstract excerpt
BACKGROUND: Prolonged antiviral treatment results in selection and accumulation of resistant strains in quasispecies pool in hepatitis B virus (HBV) infection. OBJECTIVES: The aim of this study was to characterise a novel HBV pattern which shows resistance to lamivudine, adefovir dipivoxil and entecavir using in vitro phenoyping assay. STUDY DESIGN: A male 36 years old patient diagnosed with anti HBe-positive...
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