Article
Molecular epidemical characteristics of Lamivudine resistance mutations of HBV in southern China.
Medical science monitor : international medical journal of experimental and clinical research - 1 Oct 2011
Li Si-Yue, Qin Li, Zhang Lei, Song Xing-Bo, Zhou Yi, Zhou Juan, Lu Xiao-Jun, Cao Ju, Wang Lan-Lan, Wang Jun, Ying Bin-Wu
Abstract excerpt
BACKGROUND: Lamivudine (LMV), as the preferred oral drug for use in treatment of HBV, always results in development of resistance mutations after long-term treatment. In this study we investigated chronic hepatitis B (CHB) patients in southern China to determine whether different HBV genotypes affect the incidence of LMV resistance mutations. MATERIAL/METHODS: The study recruited 185 CHB patients living in...
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