Article
Antiviral drug resistance: clinical consequences and molecular aspects.
Seminars in liver disease - 1 May 2006
Bartholomeusz Angeline, Locarnini Stephen A
Abstract excerpt
Antiviral drug resistance now poses a major problem for the management of patients with chronic hepatitis B. In theory, resistance may be prevented if a sufficiently potent antiviral drug, or combination of antiviral agents, is used that prevents viral replication and thereby the ongoing selection of hepatitis B virus quasispecies. Emergence of drug resistance in patients with hepatitis B generally results in...
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