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Article

Common genetic variants in Wnt signaling pathway genes as potential prognostic biomarkers for colorectal cancer.

PloS one - 1 Jan 2013

Ting Wen-Chien, Chen Lu-Min, Pao Jiunn-Bey, Yang Ying-Pi, You Bang-Jau, Chang Ta-Yuan, Lan Yu-Hsuan, Lee Hong-Zin, Bao Bo-Ying

Abstract excerpt

Compelling evidence has implicated the Wnt signaling pathway in the pathogenesis of colorectal cancer. We assessed the use of tag single nucleotide polymorphisms (tSNPs) in adenomatous polyposis coli (APC)/β-catenin (CTNNB1) genes to predict outcomes in patients with colorectal cancer. We selected and genotyped 10 tSNP to predict common variants across entire APC and CTNNB1 genes in 282 colorectal cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23405266
DOI: 10.1371/journal.pone.0056196
PMCID: PMC3566082

Genes

APC
CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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