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Article

Wnt-11 as a Potential Prognostic Biomarker and Therapeutic Target in Colorectal Cancer

28 Jun 2019

Abstract excerpt

The expression of the secreted factor Wnt-11 is elevated in several types of cancer, including colorectal cancer, where it promotes cancer cell migration and invasion. Analysis of colorectal cancer gene expression databases associated WNT11 mRNA expression with increased likelihood of metastasis in a subset of patients. WNT11 expression was correlated with the expression of the Wnt receptors FZD6, RYK, and PTK7,...

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PMID: 31261741
DOI: 10.3390/cancers11070908

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