Article
The genetic factors associated with Wnt signaling pathway in colorectal cancer.
Life sciences - 1 Sept 2020
Aghabozorgi Amirsaeed Sabeti, Ebrahimi Reyhane, Bahiraee Alireza, Tehrani Sadra Samavarchi, Nabizadeh Fatemeh, Setayesh Leila, Jafarzadeh-Esfehani Reza, Ferns Gordon A, Avan Amir, Rashidi Zahra
Abstract excerpt
Colorectal cancer (CRC) is a common cancer with poor prognosis and high mortality. There is growing information about the factors involved in the pathogenesis of CRC. However, the knowledge of the predisposing factors is limited. The development of CRC is strongly associated with the Wingless/Integrated (Wnt) signaling pathway. This pathway comprises several major target proteins, including LRP5/6, GSK3β,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.