Article
The impact of HLA-E polymorphisms on relapse following allogeneic hematopoietic stem cell transplantation.
Leukemia research - 1 May 2013
Hosseini Ehteramolsadat, Schwarer Anthony P, Jalali Arash, Ghasemzadeh Mehran
Abstract excerpt
Since relapse following allogeneic hematopoietic stem cell transplantation (HSCT) can be due to the escape of the residual malignant cells from the graft-versus-leukemia (GvL) effect and given the role of NK cells in GvL and the importance of HLA-E in the modulation of NK cell function, we investigated whether polymorphisms of HLA-E molecule could impact on the incidence of relapse and the improvement of...
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