Article
HLA-E genotyping and its relevance in kidney transplantation outcome.
HLA - 1 May 2020
de Miranda Bruna L M, Gelmini Geórgia F, Risti Matilde, Hauer Vanessa, da Silva José Samuel, Roxo Valéria M M S, Bicalho Maria da Graça, Malheiros Danielle
Abstract excerpt
HLA-E, a class I nonclassical HLA molecule, is expressed in all tissues and is involved in the regulation of both innate (by interaction with the CD94/NKG2 receptor expressed mainly in NK cells) and adaptive immunity (by interaction with T CD8+ cells), suggesting a possible role in the solid organ transplantation context. Transplanted patients with chronic kidney disease and their respective donors (N = 107...
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