Article
Protective Effect of HLA-E∗0101∕∗0103 Genotype in Survival of Patients After Allogeneic Hematopoietic Stem Cell Transplant.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation - 1 Aug 2021
Mardani Valandani Fatemeh, Ghorbani-Dalini Sadegh, Ramzi Mani, Aghababa Heydar, Sarshar Meysam, Haghgoo Najmeh, Azarpira Negar
Abstract excerpt
OBJECTIVES: HLA-E is located on the nonclassical major histocompatibility complex class I and acts as the ligand for natural killer cells. Consequently, it has a main role in the regulation of innate immune responses by involving cell identification by natural killer cells. Differences in expression levels among HLA-E alleles have been suggested to affect transplant outcomes. In this study, we evaluated the...
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