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Article

HLA mismatch combinations associated with decreased risk of relapse: implications for the molecular mechanism.

Blood - 19 Mar 2009

Kawase Takakazu, Matsuo Keitaro, Kashiwase Koichi, Inoko Hidetoshi, Saji Hiroh, Ogawa Seishi, Kato Shunichi, Sasazuki Takehiko, Kodera Yoshihisa, Morishima Yasuo

Abstract excerpt

The finding that the risk of relapse in hematologic malignancy decreases after allogeneic hematopoietic stem cell transplantation (HSCT) has lead to the concept of a graft-versus-leukemia (GVL) effect. However, this beneficial effect is considered to be frequently offset by graft-versus-host disease (GVHD). Thus, improving HSCT outcomes by separating GVL from GVHD is a key clinical issue. This cohort study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18997170
DOI: 10.1182/blood-2008-08-171934

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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