Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of bovine intraspecies hybridomas with initial suppressed growth.

Veterinary immunology and immunopathology - 1 Mar 1990

Olobo J O, Black S J

Abstract excerpt

Bovine B-cell hybrids were generated by fusing pokeweed mitogen (PWM) activated normal bovine peripheral blood lymphocytes (PBL) with an aminopterin-sensitive bovine B-cell line BL20. The fusion partner was derived by irradiation and growth in medium containing increasing concentrations of 6-thioguanine (6TG). Resultant cells were designated ATS/BL20. Polyethylene glycol-induced (PEG) fusion was used and hybrids...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocytes
Share to Cattle
Share to Cell Division

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Line

Share to Cell Survival

Share to Culture Media

Share to Karyotyping

Share to Mutation

Source

Identifiers

PMID: 2339500
DOI: 10.1016/0165-2427(90)90044-s

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of bovine intraspecies hybridomas with initial suppressed growth.PMID 2339500Read ↗

Generation and characterisation of bovine antigen-specific T cell lines.Semantic proximity Read ↗

Expression and production of cytokines by heterohybrids and their parental B cells in CLL.Semantic proximity Read ↗

Allelic variants of rearranged immunoglobulin heavy and light chain genes in hybridoma PTF-02 and parent myeloma.Semantic proximity Read ↗

Stable nontumorigenic phenotype of somatic cell hybrids between malignant Burkitt's lymphoma cells and autologous EBV-immortalized B cells despite induction of chromosomal breakage and loss.Semantic proximity Read ↗

CD5dim peripheral blood lymphocytes proliferate to exogenous IL-2 in the absence of antigen and kill in an NK-like manner.Semantic proximity Read ↗

Incorporation of killer functions from murine T-cytotoxic spleen cultures in somatic hybrids.Semantic proximity Read ↗

Establishment of a human B cell line that responds specifically to B cell growth factor.Semantic proximity Read ↗

Progression to persistent lymphocytosis and tumor development in bovine leukemia virus (BLV)-infected cattle correlates with impaired proliferation of CD4+ T cells in response to gag- and env-encoded BLV proteins.Semantic proximity Read ↗

Conservative mutations in the immunosuppressive region of the bovine leukemia virus transmembrane protein affect fusion but not infectivity in vivo.Semantic proximity Read ↗

Application of an immune-tolerizing procedure to generate monoclonal antibodies specific to an alternate protein isoform of bovine growth hormone.Semantic proximity Read ↗

Generation of class I MHC-restricted T-T hybridomas.Semantic proximity Read ↗

The IgG2a/IgA produced by the murine T560 B lymphoma that arose during a graft-versus-host reaction is polyreactive and somatically mutated.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.