Article
Expression and production of cytokines by heterohybrids and their parental B cells in CLL.
Leukemia & lymphoma - 1 Apr 1996
Diaw L, Lefebvre d'Hellencourt C, Cornillet I, Vuillier F, Guenounou M, Dighiero G
Abstract excerpt
Three hybrids derived from CD5+ B cell chronic lymphocytic leukemia (B-CLL) and their parental B cells were studied for phenotypic evolution, immunoglobulin (Ig), tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) secretion. When phenotypic evolution was examined, hybrids showed the loss of classical B cell markers, indicating that they follow the same pattern of phenotypic differentiation as normal...
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