Article
Generation of class I MHC-restricted T-T hybridomas.
Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 1990
Rock K L, Rothstein L, Gamble S
Abstract excerpt
In this report we describe a system for the generation of functional, class I MHC-restricted, T-T hybridomas. The BW5147 cell line was transfected with the CD8 gene. BW5147 transfectants were obtained that stably expressed CD8 and this expression was maintained after somatic cell hybridization with activated T lymphocytes. To determine whether the stable expression of CD8 would facilitate the generation of class...
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