Article
Allelic variants of rearranged immunoglobulin heavy and light chain genes in hybridoma PTF-02 and parent myeloma.
Genetica - 1 Jan 1991
Deyev S M, Urakov D N, Stepchenko A G, Polanovsky O L
Abstract excerpt
The hybridoma PTF-02 secretes an antibody against pig transferrin. Rearranged genes for heavy and light immunoglobulin chains have been studied in the genomes of this hybridoma and in the parent myeloma P3-X63.Ag8.653. The hybridoma was shown to contain three rearranged allelic variants of the he...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Gene Rearrangement, B-Lymphocyte
- Genes, Immunoglobulin
- Genetic Variation
- Hybridomas
- Immunoglobulin Heavy Chains
- Immunoglobulin Light Chains
- Immunoglobulin kappa-Chains
- Molecular Sequence Data
- Pedigree
- Tumor Cells, Cultured