Article
The G84E mutation of HOXB13 is associated with increased risk for prostate cancer: results from the REDUCE trial.
Carcinogenesis - 1 Jun 2013
Chen Zhuo, Greenwood Celia, Isaacs William B, Foulkes William D, Sun Jielin, Zheng Sigun L, Condreay Lynn D, Xu Jianfeng
Abstract excerpt
A novel rare mutation, homeobox B13 (HOXB13) G84E, was reported to co-segregate with prostate cancer (PCa) in hereditary PCa families and associate with PCa risk in unrelated cases and controls. In this study, we aim to compare the G84E mutation frequency among subjects of different races/ethnicities from various geographic regions in the world and to assess its risk for developing PCa, in the Reduction by...
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