Article
HOXB13 mutations in a population-based, case-control study of prostate cancer.
The Prostate - 1 May 2013
Stott-Miller Marni, Karyadi Danielle M, Smith Tiffany, Kwon Erika M, Kolb Suzanne, Stanford Janet L, Ostrander Elaine A
Abstract excerpt
BACKGROUND: Prostate cancer (PC) is the most frequently diagnosed non-skin malignancy in men in the Western world, yet few disease-associated mutations have been found. Recently, a low frequency recurring mutation in the HOXB13 gene was reported among both hereditary PC families and men from the general population. MATERIALS AND METHODS: We determined the distribution and frequency of the G84E HOXB13 variant in...
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