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Homeobox B13 G84E Mutation and Prostate Cancer Risk

8 Dec 2018

Abstract excerpt

BACKGROUND: The homeobox B13 (HOXB13) G84E mutation has been recommended for use in genetic counselling for prostate cancer (PCa), but the magnitude of PCa risk conferred by this mutation is uncertain. OBJECTIVE: To obtain precise risk estimates for mutation carriers and information on how these vary by family history and other factors. DESIGN, SETTING, AND PARTICIPANTS: Two-fold: a systematic review and...

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PMID: 30527799
DOI: 10.1016/j.eururo.2018.11.015

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