Article
Response regulator-mediated MAPKKK heteromer promotes stress signaling to the Spc1 MAPK in fission yeast.
Molecular biology of the cell - 1 Apr 2013
Morigasaki Susumu, Ikner Aminah, Tatebe Hisashi, Shiozaki Kazuhiro
Abstract excerpt
The Spc1 mitogen-activated protein kinase (MAPK) cascade in fission yeast is activated by two MAPK kinase kinase (MAPKKK) paralogues, Wis4 and Win1, in response to multiple forms of environmental stress. Previous studies identified Mcs4, a "response regulator" protein that associates with the MAP...
Topics
- Amino Acid Sequence
- Cell Cycle Proteins
- Immunoblotting
- MAP Kinase Kinase Kinases
- Mitogen-Activated Protein Kinase Kinases
- Mitogen-Activated Protein Kinases
- Molecular Sequence Data
- Mutation
- Osmotic Pressure
- Phosphorylation
- Protein Binding