Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast.

doi:10.1038/378739a0

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Article

Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast.

Nature - 14 Dec 1995

Shiozaki K, Russell P

Abstract excerpt

In fission yeast the onset of mitosis is brought about by Cdc2/Cdc13 kinase, which is inhibited by the Wee1/Mik1 tyrosine kinases and activated by Cdc25 tyrosine phosphatase. This control network integrates many signals, including those that monitor DNA replication, DNA damage and cell size. We report here that a fission yeast MAP kinase pathway links the cell-cycle G2/M control with changes in the extracellular...

Topics

Amino Acid Sequence
Animals
Base Sequence
Calcium-Calmodulin-Dependent Protein Kinases
Cell Cycle
Cell Cycle Proteins
Cloning, Molecular
DNA Primers
Mitogen-Activated Protein Kinases
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phosphorylation

Protein Tyrosine Phosphatases

Schizosaccharomyces

Schizosaccharomyces pombe Proteins

Sequence Homology, Amino Acid

Tyrosine

Source

Open in PubMed

Identifiers

PMID: 7501024
DOI: 10.1038/378739a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7501024-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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