Article
Identification of Cdc37 as a novel regulator of the stress-responsive mitogen-activated protein kinase.
Molecular and cellular biology - 1 Aug 2003
Tatebe Hisashi, Shiozaki Kazuhiro
Abstract excerpt
Eukaryotic cells utilize multiple mitogen-activated protein kinases (MAPKs) to transmit various extracellular stimuli to the nucleus. A subfamily of MAPKs that mediates environmental stress stimuli is also called stress-activated protein kinase (SAPK), which has crucial roles in cellular survival under stress conditions as well as inflammatory responses. Here we report that Cdc37, an evolutionarily conserved...
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