Article
Mcs4 mitotic catastrophe suppressor regulates the fission yeast cell cycle through the Wik1-Wis1-Spc1 kinase cascade.
Molecular biology of the cell - 1 Mar 1997
Shiozaki K, Shiozaki M, Russell P
Abstract excerpt
Spc1 in Schizosaccharomyces pombe is a member of the stress-activated protein kinase family, an evolutionary conserved subfamily of mitogen-activated protein kinases (MAPKs). Spc1 is activated by a MAPK kinase homologue, Wis1, and negatively regulated by Pyp1 and Pyp2 tyrosine phosphatases. Mutat...
Topics
- Amino Acid Sequence
- Calcium-Calmodulin-Dependent Protein Kinases
- Cell Cycle
- Cell Cycle Proteins
- Fungal Proteins
- G2 Phase
- Gene Deletion
- Gene Expression Regulation
- Genes, Suppressor
- Mitogen-Activated Protein Kinase Kinases
- Mitogen-Activated Protein Kinases
- Molecular Sequence Data
- Mutation
- Protein Serine-Threonine Kinases