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Article

The Win1 mitotic regulator is a component of the fission yeast stress-activated Sty1 MAPK pathway.

Molecular biology of the cell - 1 Feb 1998

Shieh J C, Wilkinson M G, Millar J B

Abstract excerpt

The fission yeast Sty1 mitogen-activated protein (MAP) kinase (MAPK) and its activator the Wis1 MAP kinase kinase (MAPKK) are required for cell cycle control, initiation of sexual differentiation, and protection against cellular stress. Like the mammalian JNK/SAPK and p38/CSBP1 MAPKs, Sty1 is activated by a range of environmental insults including osmotic stress, hydrogen peroxide, UV light, menadione, heat...

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Identifiers

PMID: 9450957
DOI: 10.1091/mbc.9.2.311
PMCID: PMC25255

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Source receipt: pubmed, retrieved 7 Sept 2026.

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The Win1 mitotic regulator is a component of the fission yeast stress-activated Sty1 MAPK pathway.PMID 9450957Read ↗

The fission yeast mitotic regulator win1+ encodes an MAP kinase kinase kinase that phosphorylates and activates Wis1 MAP kinase kinase in response to high osmolarity.Semantic proximity Read ↗

Mcs4 mitotic catastrophe suppressor regulates the fission yeast cell cycle through the Wik1-Wis1-Spc1 kinase cascade.Semantic proximity Read ↗

The Srk1 protein kinase is a target for the Sty1 stress-activated MAPK in fission yeast.Semantic proximity Read ↗

Peroxide sensors for the fission yeast stress-activated mitogen-activated protein kinase pathway.Semantic proximity Read ↗

Response regulator-mediated MAPKKK heteromer promotes stress signaling to the Spc1 MAPK in fission yeast.Semantic proximity Read ↗

Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast.Semantic proximity Read ↗

Activation and regulation of the Spc1 stress-activated protein kinase in Schizosaccharomyces pombe.Semantic proximity Read ↗

The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast.Semantic proximity Read ↗

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Cold induces stress-activated protein kinase-mediated response in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

Pyp1 and Pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell size at division in fission yeast.Semantic proximity Read ↗

Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1.Semantic proximity Read ↗

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